Who is eligible

Aged 18-70 years
CLBP in the area L1 to S1 associated with vertebral body endplate bone oedema (Modic 1) or vertebral body endplate bone oedema and fat (Modic 1 and 2), at a single lumbar level
CLBP has lasted > 6 months
Moderate-severe pain, back pain greater than leg pain
Moderate-severe disability
There is no clear alternative cause for back pain
Failure of standard of care therapies
The target lumbar disc must not have lost more than half its anticipated height at its centre
Further information can be found at clinicaltrials.gov
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